Dr Maria Costello

Bio:

Dr Maria Costello is a Consultant Geriatrician and Senior Lecturer in Geriatric Medicine within University Hospital Galway and University of Galway. She is clinically working within the integrated care programme for older persons (ICPOP) covering West Galway City and County. She has a strong research portfolio and was awarded her PhD entitled “Importance of the Caregiver in Lifestyle Interventions for Cognitive Impairment” in 2021 under the supervision of Professor Martin O Donnell and Professor Michelle Canavan. She have been an active member of a meta-analysis working group and neurovascular research group which has also resulted in several international publications. To date she has published over thirty original articles (including publications in JAMA and NEJM) over fourty abstracts which have been presented at national and international conferences. She has completed formal modules in biostatistics, observational research, research methods for randomised controlled trials and health research and evaluation methods and has been a peer reviewer for HRB Open Research. Her goals are to provide high-quality patient care, and further develop collaborative relationships with multidisciplinary, hospital and University-based colleagues who are equally committed to providing excellent care to the older population.

Clinical Trials:

• PREVENT AD sub-investigator SJH 2021

• Sub-investigator EVOKE and EVOKE+ SJH 2021

• Sub-investigator CONVINCE Trial UHG 2019-2021

• Sub-investigator CONVINCE Trial UHL 2017-2018

• Sub-investigator for the STEADFAST Trial UHG 2016-2017

• Sub-investigator for the APECS Study UHG 2016-2017

Top Five Publications

Role of Proxy Respondents in International Stroke Research: Experience of the INTERSTROKE Study. Costello MM, Judge C, Reddin C, Rangarajan S, Langhorne P, Zhang H, Iversen HK, Xavier D, Smyth A, Canavan MD, Yusuf S, O'Donnell MJ.

Neuroepidemiology. 2022 Jul 11. doi: 10.1159/000525510. Online ahead of print. PMID: 35817005

Are clinical trials randomising households to lifestyle interventions to delay cognitive decline feasible? A pilot study to determine the beliefs, preferences, and deterrents for households impacted by dementia based on semi-structured interviews. Costello MM, Mc Carthy CE, Bosch J, Robinson S, McDermott C, Canavan MD, O'Donnell MJ.

BMC Geriatr. 2022 Apr 13;22(1):322. doi: 10.1186/s12877-022-02941-8. PMID: 35418013; PMCID: PMC9005908.

Association of Blood Pressure Lowering with Incident Dementia or Cognitive Impairment: A Systematic Review and Meta-analysis. Hughes D, Judge C, Murphy R, Loughlin E, Costello M, Whiteley W, Bosch J, O'Donnell MJ, Canavan M.

JAMA. 2020 May 19;323(19):1934-1944. doi: 10.1001/jama.2020.4249. PMID: 32427305

Effect of non-vitamin-K oral anticoagulants on stroke severity compared to warfarin: a meta-analysis of randomized controlled trials. Costello M, Murphy R, Judge C, Ruttledge S, Gorey S, Loughlin E, Hughes D, Nolan A, O'Donnell MJ, Canavan M.

Eur J Neurol. 2020 Mar;27(3):413-418. doi: 10.1111/ene.14134. Epub 2020 Jan 8.

“Chronic Splenic Brucellosis” Maria Costello, Mark J Enzler June 16 2016

Images in Clinical Medicine, New England Journal of Medicine 10.1056/NEJMicm151101

Current Research Interests:

Dementia; Stroke; Frailty; Falls; Integrated care for older adults

Awards and Notable Achievements:

2021 Michael J O Donnell award in recognition of outstanding research by a registrar in medicine

2021 Awarded Higher Education Authority costed extension bursary for research disrupted by the COVID-19 pandemic

2020 Recipient of Development Spark Seed funding award from the National Doctors Training and Planning (NDTP) for “MIND: Multidisciplinary Innovation to Improve Door to Needle Time”.

2019 Recipient of Development funding award from National dementia Office for acute hospital Quality Improvement project for University Hospital Galway

2019 Michael J O Donnell award in recognition of outstanding research by a registrar in medicine