Mass Spectrometry Core
TSD Mass Spectrometry Services
Targeted mass spectrometry is a gold standard technique for precise compound quantification and is widely used in industry and clinical laboratories. This powerful technology enables efficient translation from research discoveries to commercial applications. Operated by an expert team of Senior Technical Officers, our Core Facility supports diverse projects across biology, chemistry and environmental science. Researchers gain access to cutting-edge instrumentation, specialised training and expert guidance to ensure high-quality data generation, robust analysis and maximum research impact.
Our Service Portfolio Includes:
We provide targeted and quantitative analysis of small molecules using robust triple quadrupole (QqQ) mass spectrometers, supporting a wide range of applications in research and development.
• Assay Development & MS Analysis: Custom assay design and implementation using optimized MRM methods.
• Data Analysis: We support data processing for MS experiments. We recommend discussing your needs in advance, as extended analysis may be available on a case-by-case basis.
• Consultation: We offer guidance on experimental design, method development and workflow optimization.
• Training: Hands-on training on for assay development and data analysis.
• Sample Preparation Support: Assistance with sample prep, including protocol development provided on a case-by-case basis.
*Rates for Assisted and assay development are also available. Please reach out for further details.
Our Equipment Portfolio Includes:
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SCIEX 4500 QTRAP Agilent 6460 A robust and versatile triple quadrupole mass spectrometer capable of supporting multiplexed analysis of analytes with high-selectivity and low-background noise.
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Access Charges:
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Academic Rates per Hour for Autonomous use* |
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Sciex QTRAP 4500 system |
€42 |
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Agilent 6460 triple quadrupole |
€24 |
*Rates for Assisted use are also available. Please reach out for further details.
Design and Consulting rates are available upon request upon project outline.
Industry rates are available upon request and project consultation.
Targeted Mass Spectrometry:
Multiple Reaction Monitoring (MRM) is a targeted mass spectrometry (MS) technique for quantifying small molecules—including lipids, metabolites and chemical compounds. MRM is carried out using triple quadrupole (QqQ) mass spectrometers, a gold standard platform for targeted quantification. In a typical MRM experiment, analytes are first separated by HPLC, then ionized and introduced into a triple quadrupole mass spectrometer, where the first quadrupole (Q1) isolates precursor ions, the second quadrupole (Q2) induces collision‐activated dissociation, and the third quadrupole (Q3) selectively transmits target fragment ions for quantitative detection.
Contact
Email: massspec@universityofgalway.ie
This facility is part of the Technology Services Directorate (TSD).
