The GNC host Genes, Brain and Behavior 2023 meeting at University of Galway

The Galway Neuroscience Centre (GNC) in collaboration with the International Behavioural and Neural Genetics Society (IBANGS) hosted the Genes, Brain and Behavior 2023 conference in the Human Biology Building in University of Galway between 22-25 May. The conference was attended by 130 delegates, including 100 from overseas, who presented research on the genetic basis of a wide range of behaviours and brain disorders together with the underlying neuronal mechanisms using diverse species. The goal of this field is to understand the molecular pathways through which genes together with the environment affect behaviour. Prof Eilís Dowd from University of Galway delivered the Keynote Address on “Cellular Brain Repair for Parkinson’s Disease” followed by a screening of "Feats of Modest Valour" and a panel discussion on Parkinson’s disease and Science on Screen. The Presidential Speaker was Dr Jamaji Nwanaji-Enwerem from University of Emory on “Environments and Human Heath”.

Dr Derek Morris (Chair of the Local Organizing Committee (LOC)) delivered an Educational Workshop on “Functional Interpretation of GWAS data”. Two symposia at the conference were led by GNC researchers and members of the LOC; “Genes, Circuits, and Environment in Chronic Pain” chaired by Dr Michelle Roche from the Centre for Pain Research and “The Role of Inflammation in Psychosis” chaired by Dr Declan McKernan from the Centre for Neuroimaging, Cognition and Genomics (NICOG). Multiple other postdoctoral and PhD researchers from the GNC at University of Galway delivered oral and poster presentations. Other members of the LOC included Prof Dara Cannon and Prof Gary Donohoe.

The GNC also awarded bursaries to support the attendance of the following early career researchers at the meeting. All Early career researchers presented posters at the meeting

Name

Unit

Abstract Title

Deema Ali

School of Biological and Chemical Sciences

MEF2C Dysregulation and its Association with Neuropsychiatric Disorders and Cognitive Function in Human Neural Cells

Giulia Comini

Discipline of Pharmacology & Therapeutics

Biomaterial enhanced brain repair in Parkinsonian rats: an early comparison between cyclosporine immunosuppressed Sprague Dawley rats and athymic nude rats

Shane Crinion

School of Biological and Chemical Sciences

Mendelian randomisation identifies gene expression alterations associated with chronotype and neuropsychiatric disorders

Shir Dahan

Discipline of Anatomy

The effect of genetic risk for schizophrenia on cognitive performance

Catherine Healy

Discipline of Pharmacology & Therapeutics

Behavioural characterisation of an incisional wound model, and investigation of associated alterations in the endocannabinoid system

Dijana Ostojic

School of Biological and Chemical Sciences

The impact of complement-based polygenic risk score for schizophrenia on cognitive performance via cortical thickness in schizophrenia and healthy adults

Kaushik Narasimhan

Discipline of Pharmacology & Therapeutics

In vitro assessment of biomaterial microcarriers for sustained delivery of dopaminergic neurotrophins in the context of enhancing cell-based brain repair in the Parkinsonian rat brain

Saahithh Redddi Patlola

Discipline of Pharmacology & Therapeutics

Elevated mRNA expression and activity of Toll-like receptor and cytokine in patients with schizophrenia